Characterization of a novel Taenia solium oncosphere antigen
نویسندگان
چکیده
منابع مشابه
Prevalence of antibodies to unique Taenia solium oncosphere antigens in taeniasis and human and porcine cysticercosis.
The presence of two oncosphere antigens (OAs) of 22.5 and 31.3 kD in whole and excretory/secretory (ES) OA preparations of both Taenia solium and T. saginata or in antigen preparations from T. solium metacestodes or immature tapeworms was assessed. This included an evaluation of whether antibodies to other cestodes cross-reacted to these OAs. The OAs were present in whole oncosphere extract and...
متن کاملTaenia solium oncosphere adhesion to intestinal epithelial and Chinese hamster ovary cells in vitro.
The specific mechanisms underlying Taenia solium oncosphere adherence and penetration in the host have not been studied previously. We developed an in vitro adhesion model assay to evaluate the mechanisms of T. solium oncosphere adherence to the host cells. The following substrates were used: porcine intestinal mucosal scrapings (PIMS), porcine small intestinal mucosal explants (PSIME), Chinese...
متن کاملMolecular characterization and diagnostic value of Taenia solium low-molecular-weight antigen genes.
Neurocysticercosis (NCC) caused by infection with the larvae of Taenia solium is an important cause of neurological disease worldwide. In order to establish an enzyme-linked immunosorbent assay (ELISA) for this infection using recombinant proteins, we carried out molecular cloning and identified four candidates as diagnostic antigens (designated Ag1, Ag1V1, Ag2, and Ag2V1). Except for Ag2V1, th...
متن کاملControl of Taenia solium.
Control or eradication of Taenia solium cysticercosis has been achieved to date only in Europe and North America. Significant improvements in sanitary conditions and developing functional slaughterhouse control systems were primarily responsible for control in these regions. Conversely, in endemic areas of developing countries control is limited by economic and sanitary conditions: the life cyc...
متن کاملTaenia solium cysticercosis.
Cysticercosis, the infection of the larval tissue stage of the pork tapeworm, Taenia solium, is endemic to most developing countries and increasingly is seen in industrialized countries because of immigration. Human infection is a major cause of acquired epilepsy, and porcine infection causes important economic losses to farm workers. Clinical manifestations vary because of the variable number,...
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ژورنال
عنوان ژورنال: Molecular and Biochemical Parasitology
سال: 2007
ISSN: 0166-6851
DOI: 10.1016/j.molbiopara.2007.07.017